{"type":"standard","title":"Mitochondrial complex II deficiency","displaytitle":"Mitochondrial complex II deficiency","namespace":{"id":0,"text":""},"wikibase_item":"Q23542368","titles":{"canonical":"Mitochondrial_complex_II_deficiency","normalized":"Mitochondrial complex II deficiency","display":"Mitochondrial complex II deficiency"},"pageid":64381261,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/5/5a/SuccDeh.svg/330px-SuccDeh.svg.png","width":320,"height":241},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/5/5a/SuccDeh.svg/665px-SuccDeh.svg.png","width":665,"height":500},"lang":"en","dir":"ltr","revision":"1253728743","tid":"e45c1960-9478-11ef-918a-a4fb4810df25","timestamp":"2024-10-27T15:34:02Z","description":"Medical condition","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Mitochondrial_complex_II_deficiency","revisions":"https://en.wikipedia.org/wiki/Mitochondrial_complex_II_deficiency?action=history","edit":"https://en.wikipedia.org/wiki/Mitochondrial_complex_II_deficiency?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Mitochondrial_complex_II_deficiency"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Mitochondrial_complex_II_deficiency","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Mitochondrial_complex_II_deficiency","edit":"https://en.m.wikipedia.org/wiki/Mitochondrial_complex_II_deficiency?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Mitochondrial_complex_II_deficiency"}},"extract":"Mitochondrial complex II deficiency, also called CII deficiency, is a rare mitochondrial disease caused by deficiency of mitochondrial complex II, also known as Succinate dehydrogenase (SDH). SDH plays a key role in metabolism; the catalytic end, made up of SDHA and SDHB oxidizes succinate to fumarate in the tricarboxylic acid (TCA) cycle. The electrons from this reaction then reduce FAD to FADH2, which ultimately reduces ubiquinone to ubiquinol in the mitochondrial electron transport chain. As of 2020, about 61 cases have been reported with genetic studies, but there are also documented cases of CII deficiencies as determined by biochemical and histological analysis without genetic studies.","extract_html":"
Mitochondrial complex II deficiency, also called CII deficiency, is a rare mitochondrial disease caused by deficiency of mitochondrial complex II, also known as Succinate dehydrogenase (SDH). SDH plays a key role in metabolism; the catalytic end, made up of SDHA and SDHB oxidizes succinate to fumarate in the tricarboxylic acid (TCA) cycle. The electrons from this reaction then reduce FAD to FADH2, which ultimately reduces ubiquinone to ubiquinol in the mitochondrial electron transport chain. As of 2020, about 61 cases have been reported with genetic studies, but there are also documented cases of CII deficiencies as determined by biochemical and histological analysis without genetic studies.
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{"fact":"Your cat's heart beats at a rate almost double that of yours, from 110-140 beats per minute.","length":92}
{"type":"standard","title":"Eglinton Country Park","displaytitle":"Eglinton Country Park","namespace":{"id":0,"text":""},"wikibase_item":"Q5348071","titles":{"canonical":"Eglinton_Country_Park","normalized":"Eglinton Country Park","display":"Eglinton Country Park"},"pageid":13200316,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/e/e7/Eglintonparksign.JPG/330px-Eglintonparksign.JPG","width":320,"height":239},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/e/e7/Eglintonparksign.JPG","width":2288,"height":1712},"lang":"en","dir":"ltr","revision":"1282360399","tid":"6707e20b-09cd-11f0-a45b-ee624b70af72","timestamp":"2025-03-25T23:03:45Z","description":"Country park in North Ayrshire, Scotland","description_source":"local","coordinates":{"lat":55.64177778,"lon":-4.67163889},"content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Eglinton_Country_Park","revisions":"https://en.wikipedia.org/wiki/Eglinton_Country_Park?action=history","edit":"https://en.wikipedia.org/wiki/Eglinton_Country_Park?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Eglinton_Country_Park"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Eglinton_Country_Park","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Eglinton_Country_Park","edit":"https://en.m.wikipedia.org/wiki/Eglinton_Country_Park?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Eglinton_Country_Park"}},"extract":"Eglinton Country Park is located on the grounds of the old Eglinton Castle estate in Kilwinning, North Ayrshire, Scotland. Eglinton Park is situated in the parish of Kilwinning, part of the former district of Cunninghame, and covers an area of 400 ha ([98 acres ] of which are woodland. The central iconic feature of the country park is the ruined Eglinton Castle, once home to the Eglinton family and later the Montgomeries, Earls of Eglinton and chiefs of the Clan Montgomery. Eglinton Country Park is managed and maintained by North Ayrshire Council and its Ranger Service.","extract_html":"
Eglinton Country Park is located on the grounds of the old Eglinton Castle estate in Kilwinning, North Ayrshire, Scotland. Eglinton Park is situated in the parish of Kilwinning, part of the former district of Cunninghame, and covers an area of 400 ha ([98 acres ] of which are woodland. The central iconic feature of the country park is the ruined Eglinton Castle, once home to the Eglinton family and later the Montgomeries, Earls of Eglinton and chiefs of the Clan Montgomery. Eglinton Country Park is managed and maintained by North Ayrshire Council and its Ranger Service.
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{"slip": { "id": 170, "advice": "Remedy tickly coughs with a drink of honey, lemon and water as hot as you can take."}}
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